Cytotoxic effects and tolerability of gemcitabine and axitinib in a xenograft model for c-myc amplified medulloblastoma

Medulloblastoma is the most common high-grade brain tumor in childhood. Medulloblastomas with c-myc amplification, classified as group 3, are the most aggressive among the four disease subtypes resulting in a 5-year overall survival of just above 50%. Despite current intensive therapy regimens, pati...

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Detalles Bibliográficos
Autores principales: Schwinn, Stefanie, Mokhtari, Zeinab, Thusek, Sina, Schneider, Theresa, Sirén, Anna-Leena, Tiemeyer, Nicola, Caruana, Ignazio, Miele, Evelina, Schlegel, Paul G., Beilhack, Andreas, Wölfl, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263612/
https://www.ncbi.nlm.nih.gov/pubmed/34234256
http://dx.doi.org/10.1038/s41598-021-93586-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263612/
https://www.ncbi.nlm.nih.gov/pubmed/34234256
http://dx.doi.org/10.1038/s41598-021-93586-x

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