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Asymmetric reconstruction of mammalian reovirus reveals interactions among RNA, transcriptional factor µ2 and capsid proteins

Mammalian reovirus (MRV) is the prototypical member of genus Orthoreovirus of family Reoviridae. However, lacking high-resolution structures of its RNA polymerase cofactor μ2 and infectious particle, limits understanding of molecular interactions among proteins and RNA, and their contributions to vi...

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Detalles Bibliográficos
Autores principales: Pan, Muchen, Alvarez-Cabrera, Ana L., Kang, Joon S., Wang, Lihua, Fan, Chunhai, Zhou, Z. Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263624/
https://www.ncbi.nlm.nih.gov/pubmed/34234134
http://dx.doi.org/10.1038/s41467-021-24455-4