Cholesterol-dependent plasma membrane order (L(o)) is critical for antigen-specific clonal expansion of CD4(+) T cells

Early “T cell activation” events are initiated within the lipid microenvironment of the plasma membrane. Role of lipid membrane order (L(o)) in spatiotemporal signaling through the antigen receptor in T cells is posited but remains unclear. We have examined the role of membrane order (L(o))/disorder...

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Detalles Bibliográficos
Autores principales: Sengupta, Soumini, Karsalia, Ritesh, Morrissey, Amanda, Bamezai, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263698/
https://www.ncbi.nlm.nih.gov/pubmed/34234214
http://dx.doi.org/10.1038/s41598-021-93403-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263698/
https://www.ncbi.nlm.nih.gov/pubmed/34234214
http://dx.doi.org/10.1038/s41598-021-93403-5

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