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Cholesterol-dependent plasma membrane order (L(o)) is critical for antigen-specific clonal expansion of CD4(+) T cells
Early “T cell activation” events are initiated within the lipid microenvironment of the plasma membrane. Role of lipid membrane order (L(o)) in spatiotemporal signaling through the antigen receptor in T cells is posited but remains unclear. We have examined the role of membrane order (L(o))/disorder...
Autores principales: | Sengupta, Soumini, Karsalia, Ritesh, Morrissey, Amanda, Bamezai, Anil K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263698/ https://www.ncbi.nlm.nih.gov/pubmed/34234214 http://dx.doi.org/10.1038/s41598-021-93403-5 |
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