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Exosomes secreted by palmitic acid-treated hepatocytes promote LX-2 cell activation by transferring miRNA-107

Activation of hepatic stellate cells (HSCs) is a key inducer of liver fibrogenesis in nonalcoholic fatty liver disease (NAFLD). Exosomes play an important role between hepatocytes and HSCs. This study aims to explore the role of exosomes derived from palmitic acid (PA)-treated hepatocytes in regulat...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Li, Fangfang, Lai, Xiaoyang, Liu, Han, Wu, Shuting, Han, Yunqin, Shen, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263701/
https://www.ncbi.nlm.nih.gov/pubmed/34234100
http://dx.doi.org/10.1038/s41420-021-00536-7