Three dimensional modeling of biologically relevant fluid shear stress in human renal tubule cells mimics in vivo transcriptional profiles

The kidney proximal tubule is the primary site for solute reabsorption, secretion and where kidney diseases can originate, including drug-induced toxicity. Two-dimensional cell culture systems of the human proximal tubule cells (hPTCs) are often used to study these processes. However, these systems...

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Detalles Bibliográficos
Autores principales: Ross, Emily J., Gordon, Emily R., Sothers, Hanna, Darji, Roshan, Baron, Oakley, Haithcock, Dustin, Prabhakarpandian, Balabhaskar, Pant, Kapil, Myers, Richard M., Cooper, Sara J., Cox, Nancy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263711/
https://www.ncbi.nlm.nih.gov/pubmed/34234242
http://dx.doi.org/10.1038/s41598-021-93570-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263711/
https://www.ncbi.nlm.nih.gov/pubmed/34234242
http://dx.doi.org/10.1038/s41598-021-93570-5

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