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Three dimensional modeling of biologically relevant fluid shear stress in human renal tubule cells mimics in vivo transcriptional profiles
The kidney proximal tubule is the primary site for solute reabsorption, secretion and where kidney diseases can originate, including drug-induced toxicity. Two-dimensional cell culture systems of the human proximal tubule cells (hPTCs) are often used to study these processes. However, these systems...
Autores principales: | Ross, Emily J., Gordon, Emily R., Sothers, Hanna, Darji, Roshan, Baron, Oakley, Haithcock, Dustin, Prabhakarpandian, Balabhaskar, Pant, Kapil, Myers, Richard M., Cooper, Sara J., Cox, Nancy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263711/ https://www.ncbi.nlm.nih.gov/pubmed/34234242 http://dx.doi.org/10.1038/s41598-021-93570-5 |
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