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Endothelial cell-derived Apelin inhibits tumor growth by altering immune cell localization

The Apelin/APJ signalling pathway, involved in multiple physiological and pathological processes, has been attracting increasing interest recently. In our previous study, Apelin overexpression in colon26 tumor cells suppressed tumor growth by inducing vascular maturation. Here, we found that MC38 an...

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Detalles Bibliográficos
Autores principales: Hu, Liuying, Hayashi, Yumiko, Kidoya, Hiroyasu, Takakura, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263715/
https://www.ncbi.nlm.nih.gov/pubmed/34234274
http://dx.doi.org/10.1038/s41598-021-93619-5