Two human metabolites rescue a C. elegans model of Alzheimer’s disease via a cytosolic unfolded protein response

Age-related changes in cellular metabolism can affect brain homeostasis, creating conditions that are permissive to the onset and progression of neurodegenerative disorders such as Alzheimer’s and Parkinson’s diseases. Although the roles of metabolites have been extensively studied with regard to ce...

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Detalles Bibliográficos
Autores principales: Joshi, Priyanka, Perni, Michele, Limbocker, Ryan, Mannini, Benedetta, Casford, Sam, Chia, Sean, Habchi, Johnny, Labbadia, Johnathan, Dobson, Christopher M., Vendruscolo, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263720/
https://www.ncbi.nlm.nih.gov/pubmed/34234268
http://dx.doi.org/10.1038/s42003-021-02218-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263720/
https://www.ncbi.nlm.nih.gov/pubmed/34234268
http://dx.doi.org/10.1038/s42003-021-02218-7

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