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Drying and temperature induced conformational changes of nucleic acids and stallion sperm chromatin in trehalose preservation formulations

Even though dried sperm is not viable, it can be used for fertilization as long as its chromatin remains intact. In this study, we investigated drying- and temperature-induced conformational changes of nucleic acids and stallion sperm chromatin. Sperm was diluted in preservation formulations with an...

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Detalles Bibliográficos
Autores principales: Brogna, Raffaele, Fan, Juezhu, Sieme, Harald, Wolkers, Willem F., Oldenhof, Harriëtte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263733/
https://www.ncbi.nlm.nih.gov/pubmed/34234244
http://dx.doi.org/10.1038/s41598-021-93569-y