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Calmodulin-dependent KCNE4 dimerization controls membrane targeting

The voltage-dependent potassium channel Kv1.3 participates in the immune response. Kv1.3 is essential in different cellular functions, such as proliferation, activation and apoptosis. Because aberrant expression of Kv1.3 is linked to autoimmune diseases, fine-tuning its function is crucial for leuko...

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Detalles Bibliográficos
Autores principales: Roig, Sara R., Solé, Laura, Cassinelli, Silvia, Colomer-Molera, Magalí, Sastre, Daniel, Serrano-Novillo, Clara, Serrano-Albarrás, Antonio, Lillo, M. Pilar, Tamkun, Michael M., Felipe, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263776/
https://www.ncbi.nlm.nih.gov/pubmed/34234241
http://dx.doi.org/10.1038/s41598-021-93562-5