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Pharmacokinetics, pharmacodynamics, and safety of single- and multiple-dose intravenous ceftobiprole in healthy Chinese participants

BACKGROUND: Ceftobiprole is a novel β-lactam cephalosporin with activity against Gram-positive and -negative bacteria. The aim of the present study was to investigate the pharmacokinetics (PK), pharmacokinetics/pharmacodynamics (PK/PD), safety and tolerance of ceftobiprole in Chinese participants, t...

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Detalles Bibliográficos
Autores principales: Li, Wan-Zhen, Wu, Hai-Lan, Chen, Yuan-Cheng, Guo, Bei-Ning, Liu, Xiao-Fen, Wang, Yu, Wu, Ju-Fang, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263851/
https://www.ncbi.nlm.nih.gov/pubmed/34350251
http://dx.doi.org/10.21037/atm-21-588