Epigenetic reprogramming enhances the therapeutic efficacy of osteoblast‐derived extracellular vesicles to promote human bone marrow stem cell osteogenic differentiation

Extracellular vesicles (EVs) are emerging in tissue engineering as promising acellular tools, circumventing many of the limitations associated with cell‐based therapies. Epigenetic regulation through histone deacetylase (HDAC) inhibition has been shown to increase differentiation capacity. Therefore...

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Detalles Bibliográficos
Autores principales: Man, Kenny, Brunet, Mathieu Y., Fernandez‐Rhodes, Maria, Williams, Soraya, Heaney, Liam M., Gethings, Lee A., Federici, Angelica, Davies, Owen G., Hoey, David, Cox, Sophie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263905/
https://www.ncbi.nlm.nih.gov/pubmed/34262674
http://dx.doi.org/10.1002/jev2.12118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263905/
https://www.ncbi.nlm.nih.gov/pubmed/34262674
http://dx.doi.org/10.1002/jev2.12118

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