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Epigenetic reprogramming enhances the therapeutic efficacy of osteoblast‐derived extracellular vesicles to promote human bone marrow stem cell osteogenic differentiation
Extracellular vesicles (EVs) are emerging in tissue engineering as promising acellular tools, circumventing many of the limitations associated with cell‐based therapies. Epigenetic regulation through histone deacetylase (HDAC) inhibition has been shown to increase differentiation capacity. Therefore...
Autores principales: | Man, Kenny, Brunet, Mathieu Y., Fernandez‐Rhodes, Maria, Williams, Soraya, Heaney, Liam M., Gethings, Lee A., Federici, Angelica, Davies, Owen G., Hoey, David, Cox, Sophie C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263905/ https://www.ncbi.nlm.nih.gov/pubmed/34262674 http://dx.doi.org/10.1002/jev2.12118 |
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