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Effects of Altering Mitochondrial Antioxidant Capacity on Molecular and Phenotypic Drivers of Fibrocalcific Aortic Valve Stenosis

Background: While a small number of studies suggest that oxidative stress has an influential role in fibrocalcific aortic valve disease (FCAVD), the roles of specific antioxidant enzymes in progression of this disease remain poorly understood. Here, we focused on selectively altering mitochondrial-d...

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Detalles Bibliográficos
Autores principales: Roos, Carolyn M., Zhang, Bin, Hagler, Michael A., Verzosa, Grace C., Huang, Runqing, Oehler, Elise A., Arghami, Arman, Miller, Jordan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263922/
https://www.ncbi.nlm.nih.gov/pubmed/34250048
http://dx.doi.org/10.3389/fcvm.2021.694881