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Effects of Altering Mitochondrial Antioxidant Capacity on Molecular and Phenotypic Drivers of Fibrocalcific Aortic Valve Stenosis
Background: While a small number of studies suggest that oxidative stress has an influential role in fibrocalcific aortic valve disease (FCAVD), the roles of specific antioxidant enzymes in progression of this disease remain poorly understood. Here, we focused on selectively altering mitochondrial-d...
Autores principales: | Roos, Carolyn M., Zhang, Bin, Hagler, Michael A., Verzosa, Grace C., Huang, Runqing, Oehler, Elise A., Arghami, Arman, Miller, Jordan D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263922/ https://www.ncbi.nlm.nih.gov/pubmed/34250048 http://dx.doi.org/10.3389/fcvm.2021.694881 |
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