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Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model

Background: Mesenchymal stem cell (MSC)-derived exosomes (Exos) are recently proved to be a promising candidate for ulcerative colitis (UC), but the mechanism remains unclear. We investigated the effects of MSC-derived exosomal microRNA-181a (miR-181a) on gut microbiota, immune responses, and intest...

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Detalles Bibliográficos
Autores principales: Gu, Li, Ren, Feng, Fang, Xianrui, Yuan, Lianwen, Liu, Ganglei, Wang, Shalong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264068/
https://www.ncbi.nlm.nih.gov/pubmed/34249964
http://dx.doi.org/10.3389/fmed.2021.660614