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Tempo-spatial regulation of the Wnt pathway by FAM13A modulates the stemness of alveolar epithelial progenitors

BACKGROUND: Family with Sequence Similarity 13, Member A (FAM13A) gene has been consistently associated with COPD by Genome-wide association studies (GWAS). Our previous study demonstrated that FAM13A was mainly expressed in the lung epithelial progenitors including Club cells and alveolar type II e...

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Detalles Bibliográficos
Autores principales: Lin, Xin, Li, Yujun, Gong, Lu, Yun, Jeong H., Xu, Shuang, Tesfaigzi, Yohannes, Qiao, Dandi, Zhou, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264115/
https://www.ncbi.nlm.nih.gov/pubmed/34224973
http://dx.doi.org/10.1016/j.ebiom.2021.103463