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Myeloid Sarcoma Type of Acute Promyelocytic Leukemia With a Cryptic Insertion of RARA Into FIP1L1: The Clinical Utility of NGS and Bioinformatic Analyses

BACKGROUND: Acute promyelocytic leukemia (APL) is characterized by the presence of coagulopathy at onset and translocation t (15; 17) (q22; 21), meanwhile, other translocation variants of APL have also been reported. The FIP1L1–RARA fusion gene has recently been reported as a novel RARA-associated f...

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Detalles Bibliográficos
Autores principales: Wang, Yongren, Rui, Yaoyao, Shen, Ying, Li, Jian, Liu, Poning, Lu, Qin, Fang, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264125/
https://www.ncbi.nlm.nih.gov/pubmed/34249738
http://dx.doi.org/10.3389/fonc.2021.688203