Regulatory Dendritic Cells Induced by Bendamustine Are Associated With Enhanced Flt3 Expression and Alloreactive T-Cell Death

The growth factor Flt3 ligand (Flt3L) is central to dendritic cell (DC) homeostasis and development, controlling survival and expansion by binding to Flt3 receptor tyrosine kinase on the surface of DCs. In the context of hematopoietic cell transplantation, Flt3L has been found to suppress graft-vers...

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Detalles Bibliográficos
Autores principales: Molina, Megan S., Hoffman, Emely A., Stokes, Jessica, Kummet, Nicole, Smith, Kyle A., Baker, Forrest, Zúñiga, Tiffany M., Simpson, Richard J., Katsanis, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264365/
https://www.ncbi.nlm.nih.gov/pubmed/34249005
http://dx.doi.org/10.3389/fimmu.2021.699128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264365/
https://www.ncbi.nlm.nih.gov/pubmed/34249005
http://dx.doi.org/10.3389/fimmu.2021.699128

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