Catalytic Dyad Residues His41 and Cys145 Impact the Catalytic Activity and Overall Conformational Fold of the Main SARS-CoV-2 Protease 3-Chymotrypsin-Like Protease

Coronaviruses are responsible for multiple pandemics and millions of deaths globally, including the current pandemic of coronavirus disease 2019 (COVID-19). Development of antivirals against coronaviruses, including the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) responsible for COV...

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Detalles Bibliográficos
Autores principales: Ferreira, Juliana C., Fadl, Samar, Villanueva, Adrian J., Rabeh, Wael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264439/
https://www.ncbi.nlm.nih.gov/pubmed/34249864
http://dx.doi.org/10.3389/fchem.2021.692168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264439/
https://www.ncbi.nlm.nih.gov/pubmed/34249864
http://dx.doi.org/10.3389/fchem.2021.692168

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