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Pharmacokinetic comparison with different assays for simultaneous determination of cis-, trans-cefprozil diastereomers in human plasma

The purpose of this study was to compare pharmacokinetic (PK) parameters obtained using two newly developed assays, HPLC-UV and UPLC-ESI-MS/MS. Selection of assay and results obtained therefrom are very important in PK studies and can have a major impact on the PK-based clinical dose and usage setti...

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Detalles Bibliográficos
Autores principales: Jeong, Seung-Hyun, Jang, Ji-Hun, Cho, Hea-Young, Lee, Yong-Bok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264462/
https://www.ncbi.nlm.nih.gov/pubmed/34277123
http://dx.doi.org/10.1016/j.jpha.2020.07.001