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A DNA-based nanocarrier for efficient cancer therapy

The study aimed to achieve enhanced targeted cytotoxicity and cell-internalization of cisplatin-loaded deoxyribonucleic acid-nanothread (CPT-DNA-NT), mediated by scavenger receptors into HeLa cells. DNA-NT was developed with stiff-topology utilizing circular-scaffold to encapsulate CPT. Atomic force...

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Detalles Bibliográficos
Autores principales: Abbas, Muhammad, Baig, Mirza Muhammad Faran Ashraf, Zhang, Yaliang, Yang, Yu-Shun, Wu, Songyu, Hu, Yiqiao, Wang, Zhong-Chang, Zhu, Hai-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264464/
https://www.ncbi.nlm.nih.gov/pubmed/34277121
http://dx.doi.org/10.1016/j.jpha.2020.03.005