The dynamic broad epigenetic (H3K4me3, H3K27ac) domain as a mark of essential genes

Transcriptionally active chromatin is marked by tri-methylation of histone H3 at lysine 4 (H3K4me3) located after first exons and around transcription start sites. This epigenetic mark is typically restricted to narrow regions at the 5`end of the gene body, though a small subset of genes have a broa...

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Detalles Bibliográficos
Autores principales: Beacon, Tasnim H., Delcuve, Geneviève P., López, Camila, Nardocci, Gino, Kovalchuk, Igor, van Wijnen, Andre J., Davie, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264473/
https://www.ncbi.nlm.nih.gov/pubmed/34238359
http://dx.doi.org/10.1186/s13148-021-01126-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264473/
https://www.ncbi.nlm.nih.gov/pubmed/34238359
http://dx.doi.org/10.1186/s13148-021-01126-1

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