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The dynamic broad epigenetic (H3K4me3, H3K27ac) domain as a mark of essential genes
Transcriptionally active chromatin is marked by tri-methylation of histone H3 at lysine 4 (H3K4me3) located after first exons and around transcription start sites. This epigenetic mark is typically restricted to narrow regions at the 5`end of the gene body, though a small subset of genes have a broa...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264473/ https://www.ncbi.nlm.nih.gov/pubmed/34238359 http://dx.doi.org/10.1186/s13148-021-01126-1 |