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Identification of Koumine as a Translocator Protein 18 kDa Positive Allosteric Modulator for the Treatment of Inflammatory and Neuropathic Pain

Koumine is an alkaloid that displays notable activity against inflammatory and neuropathic pain, but its therapeutic target and molecular mechanism still need further study. Translocator protein 18 kDa (TSPO) is a vital therapeutic target for pain treatment, and recent research implies that there ma...

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Detalles Bibliográficos
Autores principales: Xiong, Bojun, Jin, Guilin, Xu, Ying, You, Wenbing, Luo, Yufei, Fang, Menghan, Chen, Bing, Huang, Huihui, Yang, Jian, Lin, Xu, Yu, Changxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264504/
https://www.ncbi.nlm.nih.gov/pubmed/34248642
http://dx.doi.org/10.3389/fphar.2021.692917