Dihydrosphingosine driven enrichment of sphingolipids attenuates TGFβ induced collagen synthesis in cardiac fibroblasts

The sphingolipid de novo synthesis pathway, encompassing the sphingolipids, the enzymes and the cell membrane receptors, are being investigated for their role in diseases and as potential therapeutic targets. The intermediate sphingolipids such as dihydrosphingosine (dhSph) and sphingosine (Sph) hav...

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Detalles Bibliográficos
Autores principales: Magaye, Ruth R., Savira, Feby, Xiong, Xin, Huynh, Kevin, Meikle, Peter J., Reid, Christopher, Flynn, Bernard L., Kaye, David, Liew, Danny, Wang, Bing H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264607/
https://www.ncbi.nlm.nih.gov/pubmed/34277924
http://dx.doi.org/10.1016/j.ijcha.2021.100837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264607/
https://www.ncbi.nlm.nih.gov/pubmed/34277924
http://dx.doi.org/10.1016/j.ijcha.2021.100837

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