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Three-Dimensional Genome Interactions Identify Potential Adipocyte Metabolism-Associated Gene STON1 and Immune-Correlated Gene FSHR at the rs13405728 Locus in Polycystic Ovary Syndrome

BACKGROUND: rs13405728 was identified as one of the most prevalent susceptibility loci for polycystic ovary syndrome (PCOS) in Han Chinese and Caucasian women. However, the target genes and potential mechanisms of the rs13405728 locus remain to be determined. METHODS: Three-dimensional (3D) genome i...

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Detalles Bibliográficos
Autores principales: Cao, Can-hui, Wei, Ye, Liu, Rang, Lin, Xin-ran, Luo, Jia-qi, Zhang, Qiu-ju, Lin, Shou-ren, Geng, Lan, Ye, Si-kang, Shi, Yu, Xia, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264658/
https://www.ncbi.nlm.nih.gov/pubmed/34248847
http://dx.doi.org/10.3389/fendo.2021.686054