Cargando…

Three-Dimensional Genome Interactions Identify Potential Adipocyte Metabolism-Associated Gene STON1 and Immune-Correlated Gene FSHR at the rs13405728 Locus in Polycystic Ovary Syndrome

BACKGROUND: rs13405728 was identified as one of the most prevalent susceptibility loci for polycystic ovary syndrome (PCOS) in Han Chinese and Caucasian women. However, the target genes and potential mechanisms of the rs13405728 locus remain to be determined. METHODS: Three-dimensional (3D) genome i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cao, Can-hui, Wei, Ye, Liu, Rang, Lin, Xin-ran, Luo, Jia-qi, Zhang, Qiu-ju, Lin, Shou-ren, Geng, Lan, Ye, Si-kang, Shi, Yu, Xia, Xi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264658/ https://www.ncbi.nlm.nih.gov/pubmed/34248847 http://dx.doi.org/10.3389/fendo.2021.686054

Ejemplares similares

Assessment of FSHR, AMH, and AMHRII variants in women with polycystic ovary syndrome
por: Czeczuga-Semeniuk, Ewa, et al.
Publicado: (2014)

Statistical Genomic Approach Identifies Association between FSHR Polymorphisms and Polycystic Ovary Morphology in Women with Polycystic Ovary Syndrome
por: Du, Tao, et al.
Publicado: (2015)

Follicle Stimulating Hormone Receptor (FSHR) Polymorphisms and Polycystic Ovary Syndrome (PCOS)
por: Laven, Joop S. E.
Publicado: (2019)

Polymorphisms in FSHR modulating susceptibility to polycystic ovary syndrome: an updated meta-analysis
por: Kaur, Mandeep, et al.
Publicado: (2023)

Role of Single Nucleotide Variants in FSHR, GNRHR, ESR2 and LHCGR Genes in Adolescents with Polycystic Ovary Syndrome
por: Lidaka, Lasma, et al.
Publicado: (2021)

Association between FSHR polymorphisms and polycystic ovary syndrome among Chinese women in north China
por: Wu, Xue-qing, et al.
Publicado: (2014)

Association of FSHR and DENND1A polymorphisms with polycystic ovary syndrome: a meta-analysis
por: Larsen, Celina Bakke, et al.
Publicado: (2023)

Polymorphisms rs2010963 and rs833061 of the VEGF gene in polycystic ovary syndrome
por: Vicente, Anna Luiza Silva Almeida, et al.
Publicado: (2022)

Tanshinone IIA attenuates estradiol-induced polycystic ovarian syndrome in mice by ameliorating FSHR expression in the ovary
por: Jin, Jing, et al.
Publicado: (2019)

Novel FSHR variants causing female resistant ovary syndrome
por: Khor, Shuzin, et al.
Publicado: (2019)

A genome-wide association study identified a novel genetic loci STON1-GTF2A1L/LHCGR/FSHR for bilaterality of neovascular age-related macular degeneration
por: Kawashima-Kumagai, Kyoko, et al.
Publicado: (2017)

Association Between Follicle-Stimulating Hormone Receptor (FSHR) rs6166 and Estrogen Receptor 1 (ESR1) rs2234693 Polymorphisms and Polycystic Ovary Syndrome Risk, Phenotype, and Reproductive Outcomes in an Infertile Portuguese Population
por: Vieira, Inês H, et al.
Publicado: (2023)

Association of rs13429458 and rs12478601 Single Nucleotide Polymorphisms of THADA Gene with Polycystic Ovary Syndrome
por: Naserpoor, Leila, et al.
Publicado: (2022)

Common Variant rs9939609 in Gene FTO Confers Risk to Polycystic Ovary Syndrome
por: Li, Tao, et al.
Publicado: (2013)

STON: exploring biological pathways using the SBGN standard and graph databases
por: Touré, Vasundra, et al.
Publicado: (2016)

A major QTL at the LHCGR/FSHR locus for multiple birth in Holstein cattle
por: Widmer, Sarah, et al.
Publicado: (2021)

Association of FTO gene variant rs9939609 with polycystic ovary syndrome from Gujarat, India
por: Chaudhary, Hiral, et al.
Publicado: (2023)

Inadequate detection of the FSHR complicates future research on extragonadal FSHR localization
por: Tedjawirja, Victoria N., et al.
Publicado: (2023)

STonKGs: a sophisticated transformer trained on biomedical text and knowledge graphs
por: Balabin, Helena, et al.
Publicado: (2022)

Cortical Surface Area Correlates with STON2 Gene Ser307Pro Polymorphism in First-Episode Treatment-Naïve Patients with Schizophrenia
por: Xiang, Bo, et al.
Publicado: (2013)

RS1799817 in INSR associates with susceptibility to polycystic ovary syndrome
por: Daghestani, Maha H.
Publicado: (2020)

Family-Based Association Study of rs17300539 and rs12495941 Polymorphism in Adiponectin Gene and Polycystic Ovary Syndrome in a Chinese Population
por: Sun, Xianchang, et al.
Publicado: (2017)

Polycystic ovary syndrome is linked with the fat mass obesity (FTO) gene variants rs17817449 and rs1421085 in western Saudi Arabia
por: Bakhashab, Sherin, et al.
Publicado: (2021)

Evaluating the association between single nucleotide polymorphisms in the stonin 2 (STON2) gene and keratoconus in a Han Chinese population
por: Zhang, Jing, et al.
Publicado: (2021)

Alteration in gut mycobiota of patients with polycystic ovary syndrome
por: Chen, Ke, et al.
Publicado: (2023)

Relationships of ferroptosis-related genes with the pathogenesis in polycystic ovary syndrome
por: Lin, Shuang, et al.
Publicado: (2023)

Association between CYP19 gene SNP rs2414096 Polymorphism and polycystic ovary syndrome in Chinese women
por: Jin, Jia-Li, et al.
Publicado: (2009)

Adiponectin Gene Polymorphism (rs17300539) Has No Influence on the Occurrence of Metabolic Syndrome in Women with Polycystic Ovary Syndrome
por: Nowak, Izabela, et al.
Publicado: (2021)

Impact of rs2414096 polymorphism of CYP19 gene on susceptibility of polycystic ovary syndrome and hyperandrogenism in Kashmiri women
por: Ashraf, Sairish, et al.
Publicado: (2021)

FSHR Trans-Activation and Oligomerization
por: Szymańska, Kamila, et al.
Publicado: (2018)

Autoimmunity to the Follicle-Stimulating Hormone Receptor (FSHR) and Luteinizing Hormone Receptor (LHR) in Polycystic Ovarian Syndrome
por: Schniewind, Hanna A., et al.
Publicado: (2021)

StonPy: a tool to parse and query collections of SBGN maps in a graph database
por: Rougny, Adrien, et al.
Publicado: (2023)

Association Between Single Nucleotide Polymorphisms (rs1484215 and rs6495096) in CYP11A1 Gene in Iranian Women with Polycystic Ovary Syndrome
por: Fathy, Parry, et al.
Publicado: (2023)

Association between rs1800795 polymorphism in the interleukin-6 gene and the risk of polycystic ovary syndrome: A meta-analysis
por: Chen, Linjie, et al.
Publicado: (2018)

Adipocyte Dysfunction in a Mouse Model of Polycystic Ovary Syndrome (PCOS): Evidence of Adipocyte Hypertrophy and Tissue-Specific Inflammation
por: Marino, Joseph S., et al.
Publicado: (2012)

Estrogen Receptors in Polycystic Ovary Syndrome
por: Xu, Xue-Ling, et al.
Publicado: (2021)

Screening and verification of genes related to polycystic ovary syndrome
por: Li, Xuebing, et al.
Publicado: (2023)

Biased Signaling and Allosteric Modulation at the FSHR
por: Landomiel, Flavie, et al.
Publicado: (2019)

Extragonadal FSHR Expression and Function—Is It Real?
por: Chrusciel, Marcin, et al.
Publicado: (2019)

Combined Effects of the FSHR 2039 A/G and FSHR -29 G/A Polymorphisms on Male Reproductive Parameters
por: Cannarella, Rossella, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_mjigfecin3i31bk929a2ipvhha