Plasma Extracellular Vesicles Enhance HIV-1 Infection of Activated CD4(+) T Cells and Promote the Activation of Latently Infected J-Lat10.6 Cells via miR-139-5p Transfer

HIV latency is a challenge to the success of antiretroviral therapy (ART). Hence patients may benefit from interventions that efficiently reactivate the latent virus to be eliminated by ARTs. Here we show that plasma extracellular vesicles (pEVs) can enhance HIV infection of activated CD4(+) T cells...

Descripción completa

Detalles Bibliográficos
Autores principales: Okoye, Isobel, Xu, Lai, Oyegbami, Olaide, Shahbaz, Shima, Pink, Desmond, Gao, Priscilla, Sun, Xuejun, Elahi, Shokrollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264662/
https://www.ncbi.nlm.nih.gov/pubmed/34249000
http://dx.doi.org/10.3389/fimmu.2021.697604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264662/
https://www.ncbi.nlm.nih.gov/pubmed/34249000
http://dx.doi.org/10.3389/fimmu.2021.697604

Ejemplares similares