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Plasma Extracellular Vesicles Enhance HIV-1 Infection of Activated CD4(+) T Cells and Promote the Activation of Latently Infected J-Lat10.6 Cells via miR-139-5p Transfer
HIV latency is a challenge to the success of antiretroviral therapy (ART). Hence patients may benefit from interventions that efficiently reactivate the latent virus to be eliminated by ARTs. Here we show that plasma extracellular vesicles (pEVs) can enhance HIV infection of activated CD4(+) T cells...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264662/ https://www.ncbi.nlm.nih.gov/pubmed/34249000 http://dx.doi.org/10.3389/fimmu.2021.697604 |