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Streptococcus mutans Lacking sufCDSUB Is Viable, but Displays Major Defects in Growth, Stress Tolerance Responses and Biofilm Formation

Streptococcus mutans appears to possess a sole iron-sulfur (Fe-S) cluster biosynthesis system encoded by the sufCDSUB cluster. This study was designed to examine the role of sufCDSUB in S. mutans physiology. Allelic exchange mutants deficient of the whole sufCDSUB cluster and in individual genes wer...

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Detalles Bibliográficos
Autores principales: Ellepola, Kassapa, Huang, Xiaochang, Riley, Ryan P., Bitoun, Jacob P., Wen, Zezhang Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264796/
https://www.ncbi.nlm.nih.gov/pubmed/34248879
http://dx.doi.org/10.3389/fmicb.2021.671533