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Acoustic Mist Ionization Mass Spectrometry for Ultrahigh-Throughput Metabolomics Screening

[Image: see text] Incorporating safety data early in the drug discovery pipeline is key to reducing costly lead candidate failures. For a single drug development project, we estimate that several thousand samples per day require screening (<10 s per acquisition). While chromatography-based metabo...

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Detalles Bibliográficos
Autores principales: Smith, Matthew J., Ivanov, Delyan P., Weber, Ralf J. M., Wingfield, Jonathan, Viant, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264826/
https://www.ncbi.nlm.nih.gov/pubmed/34156839
http://dx.doi.org/10.1021/acs.analchem.1c01616