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Clinical outcomes of patients with corticosteroid refractory immune checkpoint inhibitor-induced enterocolitis treated with infliximab

INTRODUCTION: Immune checkpoint inhibitors (CPIs) have changed the treatment landscape for many cancers, but also cause severe inflammatory side effects including enterocolitis. CPI-induced enterocolitis is treated empirically with corticosteroids, and infliximab (IFX) is used in corticosteroid-refr...

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Detalles Bibliográficos
Autores principales: Alexander, James L, Ibraheim, Hajir, Sheth, Bhavisha, Little, Jessica, Khan, Muhammad Saheb, Richards, Camellia, Hunter, Nikki, Chauhan, Dharmisha, Ratnakumaran, Raguprakash, McHugh, Kathleen, Pinato, David J, Nathan, Paul, Choy, Julia, Crusz, Shanthini M, Furness, Andrew, Turajlic, Samra, Pickering, Lisa, Larkin, James, Teare, Julian P, Papa, Sophie, Speight, Ally, Sharma, Anand, Powell, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264884/
https://www.ncbi.nlm.nih.gov/pubmed/34233964
http://dx.doi.org/10.1136/jitc-2021-002742