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Detection and Characterization of Single Cisplatin Adducts on DNA by Nanopore Sequencing
[Image: see text] Detection and characterization of an individual cisplatin adduct on a single DNA molecule is a demanding task. We explore the characteristic features of cisplatin adducts in the nanopore sequencing signal in aspects of dwell time, genome anchored current trace, and basecalling accu...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264939/ https://www.ncbi.nlm.nih.gov/pubmed/34250360 http://dx.doi.org/10.1021/acsomega.1c02106 |