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Detection and Characterization of Single Cisplatin Adducts on DNA by Nanopore Sequencing

[Image: see text] Detection and characterization of an individual cisplatin adduct on a single DNA molecule is a demanding task. We explore the characteristic features of cisplatin adducts in the nanopore sequencing signal in aspects of dwell time, genome anchored current trace, and basecalling accu...

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Detalles Bibliográficos
Autores principales:	Zhao, Xinjia, Liu, Yuru, Chen, Xiaoyu, Mi, Zhuang, Li, Wei, Wang, Pengye, Shan, Xinyan, Lu, Xinghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264939/ https://www.ncbi.nlm.nih.gov/pubmed/34250360 http://dx.doi.org/10.1021/acsomega.1c02106

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