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CHN1 promotes epithelial–mesenchymal transition via the Akt/GSK-3β/Snail pathway in cervical carcinoma

BACKGROUND: Metastasis and invasion are crucial in determining the mortality of cervical carcinoma (CC) patients. The epithelial–mesenchymal transition (EMT) is now a universal explanation for the mechanisms of tumor metastasis. Α-chimeric protein (α-chimaerin, CHN1) plays an important role in the r...

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Detalles Bibliográficos
Autores principales: Zhao, Haoqi, Wang, Lan, Wang, Shufang, Chen, Xihua, Liang, Min, Zhang, Xin, Wang, Jiedong, Xu, Xiangbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8264971/
https://www.ncbi.nlm.nih.gov/pubmed/34238315
http://dx.doi.org/10.1186/s12967-021-02963-7