Palmitate and Fructose Interact to Induce Human Hepatocytes to Produce Pro-Fibrotic Transcriptional Responses in Hepatic Stellate Cells Exposed to Conditioned Media

BACKGROUND/AIMS: Excessive consumption of dietary fat and sugar is associated with an elevated risk of nonalcoholic fatty liver disease (NAFLD). Hepatocytes exposed to saturated fat or sugar exert effects on nearby hepatic stellate cells (HSCs); however, the mechanisms by which this occurs are poorl...

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Detalles Bibliográficos
Autores principales: Piras, Ignazio S., Gerhard, Glenn S., DiStefano, Johanna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265013/
https://www.ncbi.nlm.nih.gov/pubmed/33095528
http://dx.doi.org/10.33594/000000288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265013/
https://www.ncbi.nlm.nih.gov/pubmed/33095528
http://dx.doi.org/10.33594/000000288

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