Cargando…

Principles of 3D compartmentalization of the human genome

Chromatin is organized in the nucleus via CTCF loops and compartmental domains. Here, we compare different cell types to identify distinct paradigms of compartmental domain formation in human tissues. We identify and quantify compartmental forces correlated with histone modifications characteristic...

Descripción completa

Detalles Bibliográficos
Autores principales: Nichols, Michael H., Corces, Victor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265014/
https://www.ncbi.nlm.nih.gov/pubmed/34192544
http://dx.doi.org/10.1016/j.celrep.2021.109330