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OTME-6. Deep sequencing reveals heterogeneity of brain metastasis-associated macrophages and microglia and uncovers their cell type-specific functions within the tumor microenvironment

Macrophages represent a highly plastic cell type,indispensable for tissue and organ homeostasis, as well as innate immunity. Basic and translational research attributed tumor-promoting functions to macrophages, and their presence is often associated to poor patient prognosis and therapy resistance....

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Detalles Bibliográficos
Autores principales: Schulz, Michael, Alekseeva, Tijna, Anthes, Julian, Macas, Jandranka, Michels, Birgitta, Möckl, Aylin, Niesel, Katja, Salamero-Boix, Anna, Stein, Stefan, Farin, Henner, Plate, Karl H, Reiss, Yvonne, Rödel, Franz, Sevenich, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265016/
http://dx.doi.org/10.1093/noajnl/vdab070.057