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Loss of RANBP3L leads to transformation of renal epithelial cells towards a renal clear cell carcinoma like phenotype

BACKGROUND: Renal cell carcinomas (RCC) are characterized by the deregulation of several hundred hyperosmolality-responsive genes. High expression of a subset of these genes including the Ran binding protein 3 like (RANBP3L) is linked to a favorable prognostic outcome in RCC. However, the cellular f...

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Detalles Bibliográficos
Autores principales: Chernyakov, Dmitry, Groß, Alexander, Fischer, Annika, Bornkessel, Nicola, Schultheiss, Christoph, Gerloff, Dennis, Edemir, Bayram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265145/
https://www.ncbi.nlm.nih.gov/pubmed/34233711
http://dx.doi.org/10.1186/s13046-021-01982-y