Cargando…
Loss of RANBP3L leads to transformation of renal epithelial cells towards a renal clear cell carcinoma like phenotype
BACKGROUND: Renal cell carcinomas (RCC) are characterized by the deregulation of several hundred hyperosmolality-responsive genes. High expression of a subset of these genes including the Ran binding protein 3 like (RANBP3L) is linked to a favorable prognostic outcome in RCC. However, the cellular f...
Autores principales: | Chernyakov, Dmitry, Groß, Alexander, Fischer, Annika, Bornkessel, Nicola, Schultheiss, Christoph, Gerloff, Dennis, Edemir, Bayram |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265145/ https://www.ncbi.nlm.nih.gov/pubmed/34233711 http://dx.doi.org/10.1186/s13046-021-01982-y |
Ejemplares similares
-
Deletion of Von Hippel–Lindau Interferes with Hyper Osmolality Induced Gene Expression and Induces an Unfavorable Gene Expression Pattern
por: Groß, Alexander, et al.
Publicado: (2020) -
The nuclear factor of activated T cells 5 (NFAT5) contributes to the renal corticomedullary differences in gene expression
por: Chernyakov, Dmitry, et al.
Publicado: (2022) -
Impact of cytotoxic agents or apoptosis stimulants on αklotho in MDCK, NRK-52E and HK2 kidney cells
por: Münz, Sina, et al.
Publicado: (2022) -
Hypertonicity-Affected Genes Are Differentially Expressed in Clear Cell Renal Cell Carcinoma and Correlate with Cancer-Specific Survival
por: Kandabarau, Siarhei, et al.
Publicado: (2019) -
Paraneoplastic Hypereosinophilia in Locally Advanced Clear Cell Renal Carcinoma
por: Ellez, Halil İbrahim, et al.
Publicado: (2023)