SynLeGG: analysis and visualization of multiomics data for discovery of cancer ‘Achilles Heels’ and gene function relationships

Achilles’ heel relationships arise when the status of one gene exposes a cell's vulnerability to perturbation of a second gene, such as chemical inhibition, providing therapeutic opportunities for precision oncology. SynLeGG (www.overton-lab.uk/synlegg) identifies and visualizes mutually exclus...

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Detalles Bibliográficos
Autores principales: Wappett, Mark, Harris, Adam, Lubbock, Alexander L R, Lobb, Ian, McDade, Simon, Overton, Ian M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Web Server Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265155/
https://www.ncbi.nlm.nih.gov/pubmed/33997893
http://dx.doi.org/10.1093/nar/gkab338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265155/
https://www.ncbi.nlm.nih.gov/pubmed/33997893
http://dx.doi.org/10.1093/nar/gkab338

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