eSkip-Finder: a machine learning-based web application and database to identify the optimal sequences of antisense oligonucleotides for exon skipping

Exon skipping using antisense oligonucleotides (ASOs) has recently proven to be a powerful tool for mRNA splicing modulation. Several exon-skipping ASOs have been approved to treat genetic diseases worldwide. However, a significant challenge is the difficulty in selecting an optimal sequence for exo...

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Detalles Bibliográficos
Autores principales: Chiba, Shuntaro, Lim, Kenji Rowel Q, Sheri, Narin, Anwar, Saeed, Erkut, Esra, Shah, Md Nur Ahad, Aslesh, Tejal, Woo, Stanley, Sheikh, Omar, Maruyama, Rika, Takano, Hiroaki, Kunitake, Katsuhiko, Duddy, William, Okuno, Yasushi, Aoki, Yoshitsugu, Yokota, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Web Server Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265194/
https://www.ncbi.nlm.nih.gov/pubmed/34104972
http://dx.doi.org/10.1093/nar/gkab442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265194/
https://www.ncbi.nlm.nih.gov/pubmed/34104972
http://dx.doi.org/10.1093/nar/gkab442

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