Streptococcus pneumoniae binds to host GAPDH on dying lung epithelial cells worsening secondary infection following influenza

Streptococcus pneumoniae (Spn) alone and during co-infection with influenza A virus (IAV) can result in severe pneumonia with mortality. Pneumococcal surface protein A (PspA) is an established virulence factor required for Spn evasion of lactoferricin and C-reactive protein-activated complement-medi...

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Detalles Bibliográficos
Autores principales: Park, Sang-Sang, Gonzalez-Juarbe, Norberto, Riegler, Ashleigh N., Im, Hansol, Hale, Yvette, Platt, Maryann P., Croney, Christina, Briles, David E., Orihuela, Carlos J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265312/
https://www.ncbi.nlm.nih.gov/pubmed/34133917
http://dx.doi.org/10.1016/j.celrep.2021.109267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265312/
https://www.ncbi.nlm.nih.gov/pubmed/34133917
http://dx.doi.org/10.1016/j.celrep.2021.109267

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