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Clinical effects of ursodeoxycholic acid on patients with ulcerative colitis may improve via the regulation of IL-23-IL-17 axis and the changes of the proportion of intestinal microflora

BACKGROUND: We aimed to evaluate the therapeutic effect of additional ursodeoxycholic acid (UDCA) with mesalazine, compared to mesalazine alone in patients with ulcerative colitis (UC). The mechanism was evaluated by monitoring the changes of IL-23-IL-17 axis and the intestinal microflora. METHODS:...

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Detalles Bibliográficos
Autores principales: Wang, Zhengjun, Chen, Jinhua, Chen, Zhiping, Xie, Longke, Wang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265401/
https://www.ncbi.nlm.nih.gov/pubmed/33835051
http://dx.doi.org/10.4103/sjg.SJG_462_20