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Phenotypic Switching of Atherosclerotic Smooth Muscle Cells is Regulated by Activated PARP1-Dependent TET1 Expression

Aim: During the development of atherosclerosis, the vascular smooth muscle cells (SMCs) undergo phenotypic switching from contractile phenotype to synthetic phenotype. This study aimed at examining the role of DNA modification mediated by the oxidative stress dependent ten eleven translocation enzym...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Chen, Xin, Wang, Ju-Kun, Li, Yu, Cui, Shi-Jun, Wang, Zhonggao, Luo, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265424/
https://www.ncbi.nlm.nih.gov/pubmed/32981917
http://dx.doi.org/10.5551/jat.55343