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Effect of Body Weight on Age at Onset in Huntington Disease: A Mendelian Randomization Study

OBJECTIVE: Weight loss is associated with clinical progression in Huntington disease (HD), but whether body weight causally affects disease onset or progression is unknown. Therefore, we aimed to assess whether genetically determined variations in body weight are causally related to age at onset in...

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Detalles Bibliográficos
Autores principales: van der Burg, Jorien M.M., Weydt, Patrick, Landwehrmeyer, Georg Bernhard, Aziz, N. Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265577/
https://www.ncbi.nlm.nih.gov/pubmed/34250226
http://dx.doi.org/10.1212/NXG.0000000000000603