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Effect of Body Weight on Age at Onset in Huntington Disease: A Mendelian Randomization Study
OBJECTIVE: Weight loss is associated with clinical progression in Huntington disease (HD), but whether body weight causally affects disease onset or progression is unknown. Therefore, we aimed to assess whether genetically determined variations in body weight are causally related to age at onset in...
Autores principales: | van der Burg, Jorien M.M., Weydt, Patrick, Landwehrmeyer, Georg Bernhard, Aziz, N. Ahmad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265577/ https://www.ncbi.nlm.nih.gov/pubmed/34250226 http://dx.doi.org/10.1212/NXG.0000000000000603 |
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