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Biotransformation of Doxorubicin Promotes Resilience in Simplified Intestinal Microbial Communities

Chemotherapeutic drugs can cause harmful gastrointestinal side effects, which may be modulated by naturally occurring members of our microbiome. We constructed simplified gut-associated microbial communities to test the hypothesis that bacteria-mediated detoxification of doxorubicin (i.e., a widely...

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Detalles Bibliográficos
Autores principales: Blaustein, Ryan A., Seed, Patrick C., Hartmann, Erica M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265622/
https://www.ncbi.nlm.nih.gov/pubmed/34192503
http://dx.doi.org/10.1128/mSphere.00068-21